A study published Wednesday in the New England Journal of Medicine found that when computers were used to help read mammograms, doctors ordered biopsies much more often, a 20 percent increase, reports CBS News medical correspondent Jon LaPook. But there was no improvement in cancer detection.
"It looks like computer-aided detection might not be working like people thought it would," said lead researcher Dr. Joshua Fenton, a family doctor at the University of California, Davis.
Known as computer-aided detection or CAD, it consists of a computer coupled with software that identifies suspicious spots on mammograms and visibly marks them.
Here's how it works. When mammograms are taken, radiologists first read the X-rays and make their own judgments. But they can then double-check with the computer system to make sure they have missed anything that's worth examining further. There usually isn't.
Computer-assisted mammography has been rapidly adopted since it was approved by the FDA in 1998, adds LaPook. But critics say it is no replacement for the trained eye.
"Our society, I think, puts a lot of weight on technology and we have a lot of hope in the promise of technology and perhaps our study highlights the importance of the human component of clinical medicine," said Dr. Joann Elmore of Harbor View Medical Center.
The researchers in this five-year study, backed by the federal government and the American Cancer Society, analyzed mammograms from medical centers in Washington state, Colorado and New Hampshire. Seven of 43 centers used CAD. The mammograms came from 222,135 women and included 2,351 who had a cancer diagnosis within a year of their tests.
The researchers found that with computerized mammography, a third more women were called back for suspicious findings and 20 percent more got biopsies
than with ordinary mammograms. That might be a good thing, if enough cancers turned up to justify the minor surgeries and anxiety surrounding them.
Yet the computerized method showed no clear capability to turn up more cancer cases than unaided readings: Four cancers were found for 고흥출장안마
every 1,000 mammograms, no matter what screening method was used. That means that CAD would give 156 more unneeded callbacks and 14 more biopsies for every additional cancer it finds. And though these extra cancers tend to be early ones that are easier to treat, many would never be threatening anyway.
Dr. Phil Evans, at the University of Texas Southwestern Medical Center, said that "most radiologists that use computer-aided mammograms understand there are many false positives."
Frustratingly, the study ultimately wasn't big enough to reach fully reliable comparisons between the rates of cancers found by the two methods. That means that bigger studies are needed to clarify whether computerized mammography finds enough additional cancers to make it worth all those false alarms and added cost. While the technology adds just $20 or so to a single mammogram, a CAD unit might cost $50,000 to $75,000.
Even so, Dr. Jay Baker, a Duke University radiologist who has studied the technology, said: "I don't think it's a huge stop sign to using CAD."
"CAD won't go away; it will have a place," agreed Dr. Ferris Hall, a mammogram specialist at Beth Israel Deaconess Medical Center, in Boston, who wrote an accompanying editorial. But he added, "This is a setback for it."
Whether computerized or not, periodic mammograms are recommended for healthy women every year or two once they reach age 40. Experts advise women to check the credentials of radiologists
at the clinic they plan to use and look for places that do a high volume.